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Showing posts with label annular-granular pattern. Show all posts
Showing posts with label annular-granular pattern. Show all posts

Tuesday, 9 February 2010

Nasal pigmented lesion


A 85-year-old woman consulted for a pigmented lesion on the tip of her nose.


Dermoscopy revealed:
  • a pseudo-pigmented network (due to the facial localisation)
  • asymmetric pigmentation of the follicular openings
  • slate gray dots disposed as annular- granular structures



Clinical and dermoscopic features were in favor of a lentigo maligna melanoma which was confirmed by a punch biopsy.



Saturday, 10 May 2008

Peppering


A 85-year-old woman consulted for a slowly enlarging pigmented lesion on her right cheek


Dermoscopy revealed a pseudonetwork which is characteristic of facial pigmented lesions.
Furthermore, dermoscopy showed multiple slate-grays dots or pepper-like granules realizing a typical an annular-granular pattern or peppering in favor of a lentigo maligna melanoma. A biopsy confirmed this diagnosis.


Peperring

Peppering or annular-granular pattern can also be present in lichen planus-like keratosis and actinic keratosis.
Some lentigo maligna melanomas exhibit this structure.

Thursday, 20 March 2008

Lentigo maligna melanoma

A 70-year-old woman consulted for this light-brown pigmented lesion on her left cervical area.

Dermoscopy revealed slate-gray dots disposed in an annular-granular pattern in favor of a lentigo maligna melanoma which was confirmed by biopsies performed on the lesion.

This case of lentigo maligna melanoma (LMM) exhibited only a feature of annular-granular pattern.



Annular-granular structures can be seen in:
  • lichen planus-like keratosis
  • actinic keratosis
The other possible features of lentigo maligna melanoma are:
  • asymmetric pigmented follicular openings
  • dark rhomboïdal structures
  • homogeneous areas
Other cases:1 2 3 4 5

Wednesday, 20 February 2008

Recurrent lentigo maligna melanoma

A 74-year-old woman consulted for this pigmented lesion on her left cheek. She had been operated on 6 years before for a lentigo maligna melanoma. The excision was complete.

A pigmentation recurred slowly 4 years after the excision.

Dermoscopy revealed a dark brown annular-granular pattern.

A biopsy confirmed the diagnosis of recurrence of the lentigo maligna melanoma and the patient was operated on for a second time.






The other possible dermoscopic signs of a lentigo maligna melanoma are:
  • asymmetric follicular openings
  • rhomboïdal structures
  • homogenous areas
  • milky red areas



The 3 main differential diagnoses of lentigo maligna melanoma
are:
  • actinic lentigo and flat seborrheic keratosis: pseudo-network, milia-like cysts, finger-print like structures, moth-eaten border or jelly-like edge (jelly sign)
  • pigmented actinic keratosis: usually presence of surface scale, broken-up pseudonetwork
  • pigmented basal cell carcinoma: blue-gray ovoïd nests, blue gray globules, leaf-like areas, spoke-wheel structures, ulcerations, arborizing vessels
It is important to know that dermoscopy of pigmented actinic keratoses can reveal the same dermoscopic structures as lentigo maligna melanoma namely rhomboïdal structures and annular-granular pattern.
In this cases dermoscopy is not sufficient to allow an accurate discrimination between a pigmented AK and a LMM, but dermoscopy helps to find the correct area for biopsy, for example the darker area.

Friday, 24 August 2007

Lentigo maligna melanoma

A 69-year-old woman consulted for a macular pigmented lesion of her right cheek. This multicoloured lesion was centered by a dark brown spot.




Dermoscopy focused on the darker area showed annular granular structures, asymetric follicular openings and rhomboidal structures very suggestive of lentigo maligna melanoma.


A biopsy was performed on the dark brown spot and revealed a lentigo maligna melanoma in situ.


The lesion was entirely removed and a graft was performed.
The pathology exam of the whole lesion revealed a breslow index at 0.46mm